May/June 2006
Page 8


Cuffitis, A New Type of Pouch Dysfunction

Pouch dysfunction after ileal pouch-anal anastomosis [J-pouch] can originate in the small intestine proximal to the pouch, the pouch itself, or the pouch outlet. During the past decade, many surgeons have adopted the doublestapled technique for pouch-anal anastomosis in restorative proctocolectomy for ulcerative colitis. This procedure leaves a 1-2 cm cuff of diseased rectal mucosa below the pouch and above the dentate line. The potential for persistent inflammation in this retained cuff has been a concern.

Thomson-Fawcett et al. evaluated biopsies and clinical parameters in 113 patients undergoing the double-stapled technique over a 2-1/2 year period. They report a 13% incidence of symptomatic cuffitis during this short period of followup. Cuffitis did not correlate with the incidence of pouchitis. They propose a diagnostic triad of symptoms (anal discomfort, anal irritation, discharge, and blood per anum), endoscopic evidence of inflammation, and acute inflammation seen at histology. Cuffitis appears to be a real entity and should be considered as a cause of pouch dysfunction after a double-stapled procedure. Fortunately it is usually not a major problem.

Editor’s note (Stillwater-Ponca City OK): Cuffitis should not be a cause of concern if the surgeon who builds the J-pouch does a complete anal mucosectomy instead of using the double-stapled technique.

SOURCE: J.S. Thompson, MD, FACS from American Journal of Gastroenterology; Stillwater-Ponca City (OK) Ostomy Outlook; Metro Halifax News. April 2006, via Inside Out On-line May/Jun 06.

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